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Work & Business

Explore BIG CHANGE reporting on Work & Business: what changed, how it works and why it matters.

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Latest reporting

188 stories
Original story: news

OpenAI acquires Orchestra Bio for drug-program coordination

OpenAI has acquired Orchestra Bio and plans to bring its drug-program coordination platform together with Rosalind. A combined product and faster treatments remain goals, not demonstrated results.

55
Original story: guide

Run a local Ollama model and check its chat API

Install Ollama, choose a downloaded model, check its terminal answers and send the same prompt to its localhost chat API. Verify the model and cloud boundary before calling the setup local-only.

502
Original story: guide

Give two agents the same reviewed memory record

Store one source-approved typed memory record, supply its exact reviewed bytes to two authorized agent sessions, then verify a conditional update and resolve conflicts.

528
Original story: guide

Turn agent output into a reviewed action register

Build a typed OpenAI Agents SDK result from your own notes, review its source evidence and meaning, then pass the accepted result to a local Markdown action register with hash readback.

546
Original story: analysis

Siemens and NVIDIA test inspection and planning AI at Erlangen

Siemens says AI systems being tested at its Erlangen plant can generate inspection imagery from digital twins and propose production plans for planners to assess. The release describes live production testing, while its productivity figures remain company-reported.

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